Empyema
Empyema - pleural; Pyothorax; Pleurisy - purulentEmpyema is a collection of pus in the space between the lung and the inner surface of the chest wall (pleural space).
Causes
Empyema is usually caused by an infection that spreads directly from the lung. It leads to a buildup of pus in the pleural space.
There can be 2 cups (1/2 liter) or more of infected fluid. This fluid puts pressure on the lungs.
Risk factors include:
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Bacterial pneumonia
Bacterial pneumonia
Pneumonia is a breathing (respiratory) condition in which there is an infection of the lung. This article covers community-acquired pneumonia (CAP). ...
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Tuberculosis
Tuberculosis
Pulmonary tuberculosis (TB) is a contagious bacterial infection that involves the lungs. It may spread to other organs.
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- Lung abscess
Abscess
An abscess is a collection of pus in any part of the body. In most cases, the area around an abscess is swollen and inflamed.
Read Article Now Book Mark Article - Trauma or injury to the chest
In rare cases, empyema can occur after thoracentesis. This is a procedure in which a needle is inserted through the chest wall to remove fluid in the pleural space for medical diagnosis or treatment.
Thoracentesis
Thoracentesis is a procedure to remove fluid from the space between the lining of the outside of the lungs (pleura) and the wall of the chest....
Symptoms
Symptoms of empyema may include any of the following:
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Chest pain, which worsens when you breathe in deeply (pleurisy)
Chest pain
Chest pain is discomfort or pain that you feel anywhere along the front of your body between your neck and upper abdomen.
Read Article Now Book Mark Article - Dry cough
Cough
Coughing is an important way to keep your throat and airways clear. But too much coughing may mean you have a disease or disorder. Some coughs are d...
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Excessive sweating, especially night sweats
Excessive sweating
Sweating is the release of liquid from the body's sweat glands. This liquid contains salt. This process is also called perspiration. Sweating helps...
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Fever and chills
Fever
Fever is the temporary increase in the body's temperature in response to a disease or illness. A child has a fever when the temperature is at or abov...
Read Article Now Book Mark Article - General discomfort, uneasiness, or ill feeling (malaise)
Malaise
Malaise is a general feeling of discomfort, illness, or lack of well-being.
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Shortness of breath
Shortness of breath
Breathing difficulty may involve:Difficult breathing Uncomfortable breathingFeeling like you are not getting enough air
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Weight loss (unintentional)
Weight loss
Unexplained weight loss is a decrease in body weight, when you did not try to lose the weight on your own. Many people gain and lose weight. Uninten...
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Exams and Tests
Your health care provider may note decreased breath sounds or an abnormal sound (friction rub) when listening to your chest with a stethoscope (auscultation).
Auscultation
Auscultation is listening to the sounds of the body during a physical examination.
Tests that may be ordered include:
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Chest x-ray (may require multiple positions)
Chest x-ray
A chest x-ray is an x-ray of the chest, lungs, heart, large arteries, ribs, and diaphragm.
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CT scan of chest
CT scan of chest
A chest CT (computed tomography) scan is an imaging method that uses x-rays to create cross-sectional pictures of the chest and upper abdomen....
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Thoracentesis
Thoracentesis
Thoracentesis is a procedure to remove fluid from the space between the lining of the outside of the lungs (pleura) and the wall of the chest....
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Pleural fluid analysis
Pleural fluid analysis
Pleural fluid analysis is a test that examines a sample of fluid that has collected in the pleural space. This is the space between the lining of th...
Treatment
The goal of treatment is to cure the infection. This involves the following:
- Placing a tube in your chest to drain the pus
- Giving you antibiotics to control the infection
If you have problems breathing, you may need surgery to help your lung expand properly.
Outlook (Prognosis)
When empyema complicates pneumonia, the risk for permanent lung damage and death goes up. Long-term treatment with antibiotics and drainage are needed.
In general, most people fully recover from empyema.
Possible Complications
Having empyema may lead to the following:
- Pleural thickening
- Reduced lung function
When to Contact a Medical Professional
Contact your provider if you develop symptoms of empyema.
Prevention
Prompt and effective treatment of lung infections may prevent some cases of empyema.
References
Broaddus VC, Light RW. Pleural effusion. In: Broaddus VC, Ernst JD, King TE, et al, eds. Murray and Nadel's Textbook of Respiratory Medicine. 7th ed. Philadelphia, PA: Elsevier; 2022:chap 108.
McCool FD. Diseases of the diaphragm, chest wall, pleura, and mediastinum. In: Goldman L, Cooney KA, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 86.
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Lungs - illustration
The major features of the lungs include the bronchi, the bronchioles and the alveoli. The alveoli are the microscopic blood vessel-lined sacks in which oxygen and carbon dioxide gas are exchanged.
Lungs
illustration
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Chest tube insertion - series - Pleural cavity
Presentation
Review Date: 8/26/2023
Reviewed By: Jatin M. Vyas, MD, PhD, Associate Professor in Medicine, Harvard Medical School; Associate in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, MA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.