Cardiovascular medications - cardiac glycosides
Cardiac glycosides include:
- Digoxin (Lanoxicaps, Lanoxin, Digibind)
- Digitoxin (Crystodigin)
Depletions
Magnesium
Every organ in the body, especially the heart, muscles, and kidneys, needs magnesium. This mineral also contributes to the makeup of teeth and bones...
Read Article Now Book Mark ArticleTaking digoxin may deplete magnesium.
Magnesium deficiency affects calcium and vitamin D levels in the body. This may cause:
- Muscle cramps
- Muscle weakness
- Irregular heartbeat
- Numbness and tingling in feet and toes
- Seizures
- Insomnia
- High blood pressure
Potassium
Potassium is a very important mineral for the proper function of all cells, tissues, and organs in the human body. It is also an electrolyte, a subs...
Read Article Now Book Mark ArticleTaking digitoxin may deplete potassium.
Symptoms of potassium deficiency include:
- Nausea and vomiting
- Tiredness
- Drowsiness
- Feeling of apprehension
- Weakness
- Muscle pain and weakness (mostly in the legs)
- Muscle cramps
- Strong, rapid or irregular heartbeat
Vitamin B1 (Thiamine)
Vitamin B1, also called thiamine or thiamin, is one of 8 B vitamins. All B vitamins help the body convert food (carbohydrates) into fuel (glucose), ...
Read Article Now Book Mark ArticleTaking digoxin may deplete thiamine.
Low levels of vitamin B1 may cause:
- Fatigue
- Nausea
- Loss of appetite
- Constipation
- Short-term memory loss
- Confusion
- Depression
Severe deficiency of vitamin B1 causes beriberi. Symptoms may include:
- Tingling or burning sensation in toes and feet
- Fluid buildup in the body (edema)
- Increased heart rate
- Heart failure
Editorial Note
The information presented here covers some of the nutrients that may be affected when you take certain medicines. If you have any of these signs and symptoms, it does not always mean you have low levels of these nutrients.
Factors that affect the level of nutrients are:
- Your medical history
- Diet
- Lifestyle
- How long you have been taking the medicine
Please talk to your health care provider. They can best address your health care needs and see if you are at risk for low levels of any nutrients.
Supporting Research
Asiedu DK. Vitamin deficiency (Hypovitaminosis). In: Ferri FF, ed. Ferri's Clinical Advisor 2017. Philadelphia, PA: Elsevier; 2017:1359-1360.
Cole JB, Roberts DJ. Cardiovascular drugs. In: Marx JA, Hockberger R, Walls R, eds. Rosen's Emergency Medicine. 8th ed. Philadelphia, PA: Elsevier Saunders; 2014:chap 152.
Dominiczak MH, Broom JI. Vitamins and minerals. In: Baynes JW, Dominiczak MH, eds. Medical Biochemistry. 4th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 11.
First Consult: Hypomagnesemia. February 20, 2013. www.clinicalkey.com/#!/content/medical_topic/21-s2.0-2001655. Accessed July 7, 2016.
Ioannou N, Sinha P, Treacher D. Acute heart failure. In: Bersten AD, Soni N, eds. Oh's Intensive Care Manual. 7th ed. Philadelphia, PA: Elsevier Butterworth-Heinemann; 2014:chap 24.
Leone KA. Calcium, magnesium, and phosphorus. In: Adams JG, ed. Emergency Medicine. 2nd ed. Philadelphia, PA: Elsevier Saunders; 2014:chap 166.
Osborn MB. Potassium. In: Adams JG, ed. Emergency Medicine. 2nd ed. Philadelphia, PA: Elsevier Saunders; 2014:chap 165.
Shenkin A, Roberts NB. Vitamins and trace elements. In: Burtis CA, Ashwood ER, Bruns DE, eds. Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. 5th ed. St. Louis, MO: Elsevier Saunders; 2012:chap 31.
Yu ASL. Disorders of magnesium and phosphorus. In: Lee G, Schafer AI, eds. Goldman's Cecil Medicine. 25th ed. Philadelphia, PA: Elsevier; 2016:chap 119.
Review Date: 9/19/2016
Reviewed By: Steven D. Ehrlich, NMD, Solutions Acupuncture, a private practice specializing in complementary and alternative medicine, Phoenix, AZ. Review provided by VeriMed Healthcare Network. Also reviewed by the A.D.A.M. Editorial team.