Fibromyalgia

Fibromyalgia is a condition in which a person has long-term pain that is spread throughout their body. The pain is most often accompanied by fatigue, sleep problems, difficulty concentrating, headaches, depression, and anxiety.

People with fibromyalgia may also have tenderness in the joints, muscles, tendons, and other soft tissues.

Causes

The cause of fibromyalgia is not known. Researchers think that it is due to a problem with how the central nervous system processes pain signals from nerves. Possible causes or triggers of fibromyalgia include:

• Physical or emotional trauma.
• Abnormal pain response: Areas in the brain that control pain may react differently in people with fibromyalgia.
• Sleep disturbances.
• Infection, such as a virus, although none has been identified.

Fibromyalgia is more common in females as compared to males. Women ages 20 to 50 are the most affected group of people.

The following conditions may be seen with fibromyalgia or have similar symptoms:

• Long-term (chronic) neck or back pain
• Long-term (chronic) fatigue syndrome

  Long-term (chronic) fatigue syndrome

  Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a long-term illness that affects many body systems. People with this illness are not ...

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• Depression

  Depression

  Depression may be described as feeling sad, blue, unhappy, miserable, or down in the dumps. Most of us feel this way at one time or another for shor...

  

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• Hypothyroidism (underactive thyroid)

  Hypothyroidism (underactive thyroid)

  Hypothyroidism is a condition in which the thyroid gland does not make enough thyroid hormone. This condition is often called underactive thyroid....

  

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• Lyme disease

  Lyme disease

  Lyme disease is a bacterial infection that is spread through the bite of one of several types of ticks.

  

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• Sleep disorders

  Sleep disorders

  Insomnia is trouble falling asleep, staying asleep (usually through the night), or waking up too early in the morning. Episodes of insomnia may come ...

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Symptoms

Widespread pain is the main symptom of fibromyalgia. Fibromyalgia appears to be on one end of a range of chronic widespread pain, which may be present in 10% to 15% of the general population. Fibromyalgia falls on the far end of that pain severity and chronicity scale and occurs in 1% to 5% of the general population.

The central feature of fibromyalgia is chronic pain in multiple sites. These sites are the head, each arm, the chest, the abdomen, each leg, the upper back and spine, and the lower back and spine (including the buttocks).

The pain may be mild to severe.

• It may feel like a deep ache, or a stabbing, burning pain.
• It may feel like it is coming from the joints, although the joints are not affected and appear normal.

People with fibromyalgia tend to wake up with body pain and stiffness. For some people, pain improves during the day and gets worse at night. Some people have pain all day long.

Pain may get worse with:

• Physical activity
• Cold or damp weather
• Anxiety and stress

Most people with fibromyalgia have at least one of these symptoms: fatigue, depressed mood, or sleep problems. Many people say that they cannot get to sleep or stay asleep, and they feel tired when they wake up.

Other symptoms in people with fibromyalgia may include:

• Irritable bowel syndrome (IBS) or gastroesophageal reflux disease (GERD)

  Irritable bowel syndrome (IBS)

  Irritable bowel syndrome (IBS) is a disorder that leads to pain in abdomen and changes in bowel movements. IBS is not the same as inflammatory bowel...

  

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• Memory and concentration problems
• Numbness and tingling in hands and feet
• Reduced ability to exercise
• Tension or migraine headaches

  Migraine headaches

  A migraine is a type of headache. It may occur with symptoms such as nausea, vomiting, or sensitivity to light and sound. In most people, a throbbi...

  

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Exams and Tests

To be diagnosed with fibromyalgia, you must have had at least 3 months of widespread pain with one or more of the following:

• Ongoing problems with sleep
• Fatigue
• Thinking or memory problems

It is not necessary for the health care provider to find tender points during a physical exam to make a diagnosis and results of the exam may be normal.

Results from blood and urine tests, and imaging tests are normal. These tests may be done to check for other conditions with similar symptoms. Studies of breathing during sleeping may be done to find out if you have a condition called sleep apnea.

Sleep apnea

Obstructive sleep apnea (OSA) is a problem in which your breathing pauses during sleep. This occurs because of narrowed or blocked airways.

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Fibromyalgia is common in every rheumatic disease and may complicate diagnoses and therapy. These disorders include:

• Rheumatoid arthritis
• Osteoarthritis
• Spondyloarthritis
• Systemic lupus erythematosus

Treatment

The goals of treatment are to help relieve pain and other symptoms, to reduce disability, and to help the person cope with the symptoms.

The first type of treatment may involve:

• Physical therapy
• Exercise and fitness program
• Stress-relief methods, including light massage and relaxation techniques

If these treatments do not work, your provider may also prescribe an antidepressant or muscle relaxant. Sometimes, combinations of medicines are helpful.

• The goal of these medicines is to improve your sleep and help you better tolerate pain.
• Medicine should be used along with exercise and behavior therapy.
• Duloxetine (Cymbalta), pregabalin (Lyrica), and milnacipran (Savella) are medicines that are approved by the US Food and Drug Administration (FDA) specifically for treating fibromyalgia.

Other medicines are also used to treat the condition, such as:

• Anti-seizure drugs, such as gabapentin
• Other antidepressants, such as amitriptyline
• Muscle relaxants, such as cyclobenzaprine
• Pain relievers, such as acetaminophen, ibuprofen, naproxen, or tramadol

If you have sleep apnea, a device called continuous positive airway pressure (CPAP) may be prescribed.

Cognitive-behavioral therapy is an important part of treatment. This therapy helps you learn how to:

• Deal with negative thoughts
• Keep a diary of pain and symptoms
• Recognize what makes your symptoms worse
• Seek out enjoyable activities
• Set limits

Complementary and alternative treatments may also be helpful. These may include:

• Tai chi
• Yoga
• Acupuncture

Support groups may also help.

Things you can do to help take care of yourself include:

• Eat a well-balanced diet.
• Avoid caffeine.
• Practice a good sleep routine to improve quality of sleep.
• Exercise regularly. Start with low-level exercise.

There is no evidence that opioids are effective in the treatment of fibromyalgia, and studies have suggested possible adverse effects.

Referral to a clinic with special expertise in diagnosing and treating fibromyalgia may be helpful.

Outlook (Prognosis)

Fibromyalgia is a long-term disorder. Sometimes, the symptoms improve. Other times, the pain may get worse and continue for months or years.

When to Contact a Medical Professional

Contact your provider if you have symptoms of fibromyalgia.

Prevention

There is no known prevention.