Renal vein thrombosis
Blood clot in the renal vein; Occlusion - renal veinRenal vein thrombosis is a blood clot that develops in the vein that drains blood from the kidney.
Blood clot
Blood clots are clumps that occur when blood hardens from a liquid to a solid. A blood clot that forms inside one of your veins or arteries is calle...
Causes
Renal vein thrombosis is an uncommon disorder. It may be caused by:
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Abdominal aortic aneurysm
Abdominal aortic aneurysm
The aorta is the main blood vessel that supplies blood to the abdomen, pelvis, and legs. An abdominal aortic aneurysm (AAA) occurs when an area of t...
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Dehydration (mostly in infants)
Dehydration
Dehydration occurs when your body does not have as much water and fluids as it needs. Dehydration can be mild, moderate, or severe, based on how much...
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Nephrotic syndrome
Nephrotic syndrome
Nephrotic syndrome is a group of symptoms and abnormal test results that include protein in the urine, low blood protein levels in the blood, high ch...
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- Scar formation with pressure on the renal vein
Renal
The term "renal" refers to the kidney. For example, renal failure means kidney failure. Related topics:Kidney diseaseKidney disease - dietKidney fai...
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Tumor
Tumor
A tumor is an abnormal growth of body tissue. Tumors can be cancerous (malignant) or noncancerous (benign).
In adults, the most common cause is nephrotic syndrome. In infants, the most common cause is dehydration.
Symptoms
Symptoms may include:
- Blood clot to the lung
- Bloody urine
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Decreased urine output
Decreased urine output
Decreased urine output means that you produce less urine than normal. Most adults make at least 500 milliliters of urine in 24 hours (a little over ...
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Flank pain or low back pain
Flank pain
Flank pain is pain in one side of the body between the upper belly area (abdomen) and the back.
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Exams and Tests
An exam may not reveal the specific problem. However, it may indicate nephrotic syndrome or other causes of renal vein thrombosis.
Tests include:
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Abdominal CT scan
Abdominal CT scan
An abdominal CT scan is an imaging method. This test uses x-rays to create cross-sectional pictures of the belly area. CT stands for computed tomog...
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Abdominal MRI
Abdominal MRI
An abdominal magnetic resonance imaging scan is an imaging test that uses powerful magnets and radio waves. The waves create pictures of the inside ...
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Abdominal ultrasound
Abdominal ultrasound
Abdominal ultrasound is a type of imaging test. It is used to look at organs in the abdomen, including the liver, gallbladder, spleen, pancreas, and...
Read Article Now Book Mark Article - Duplex Doppler exam of the renal veins
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Urinalysis may show protein in the urine or red blood cells in the urine
Urinalysis
Urinalysis is the physical, chemical, and microscopic examination of urine. It involves a number of tests to detect and measure various compounds th...
Read Article Now Book Mark ArticleProtein in the urine
The urine protein dipstick test measures the presence of all proteins, including albumin, in a urine sample. Albumin and protein can also be measured...
Read Article Now Book Mark ArticleRed blood cells in the urine
The RBC urine test measures the number of red blood cells in a urine sample.
Read Article Now Book Mark Article - X-ray of the kidney veins (venography)
Treatment
The treatment helps to prevent the formation of new clots and reduces the risk of clot traveling to other locations in the body (embolization).
You may get medicines that prevent blood clotting (anticoagulants). You may be told to rest in bed or cut down on activity for a short time.
If sudden kidney failure develops, you may need dialysis for a short period.
Dialysis
Dialysis treats end-stage kidney failure. It removes harmful substances from the blood when the kidneys cannot. This article focuses on peritoneal d...
Outlook (Prognosis)
Renal vein thrombosis most often gets better over time without lasting damage to the kidneys.
Possible Complications
Complications may include:
- Acute renal failure (especially if thrombosis occurs in a dehydrated child)
- End stage renal disease
- Blood clot moves to the lungs (pulmonary embolism)
Pulmonary embolism
A pulmonary embolus is a blockage of an artery in the lungs. The most common cause of the blockage is a blood clot.
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When to Contact a Medical Professional
Contact your health care provider if you have symptoms of renal vein thrombosis.
If you have experienced renal vein thrombosis, call your provider if you have:
- Decrease in urine output
- Blood in the urine
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Breathing problems (due to blood clot moving to your lung called pulmonary embolism)
Breathing problems
Breathing difficulty may involve:Difficult breathing Uncomfortable breathingFeeling like you are not getting enough air
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Prevention
In most cases, there is no specific way to prevent renal vein thrombosis. Keeping enough fluids in the body may help reduce risk.
Aspirin is sometimes used to prevent renal vein thrombosis in people who have had a kidney transplant. Blood thinners such as warfarin may be recommended for some people with chronic kidney disease.
References
Augustine J, Wee AC, Krishnamurthi V, Goldfarb DA. Renal insufficiency and ischemic nephropathy. In: Partin AW, Dmochowski RR, Kavoussi LR, Peters CA, eds. Campbell-Walsh-Wein Urology. 12th ed. Philadelphia, PA: Elsevier; 2021:chap 87.
DuBose TD, Santos RM. Vascular disorders of the kidney. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 116.
Greco BA, Umanath K. Renovascular hypertension and ischemic nephropathy. In: Feehally J, Floege J, Tonelli M, Johnson RJ, eds. Comprehensive Clinical Nephrology. 6th ed. Philadelphia, PA: Elsevier; 2019:chap 41.
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Kidney anatomy - illustration
The kidneys are responsible for removing wastes from the body, regulating electrolyte balance and blood pressure, and the stimulation of red blood cell production.
Kidney anatomy
illustration
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Kidney - blood and urine flow - illustration
This is the typical appearance of the blood vessels (vasculature) and urine flow pattern in the kidney. The blood vessels are shown in red and the urine flow pattern in yellow.
Kidney - blood and urine flow
illustration
-
Kidney anatomy - illustration
The kidneys are responsible for removing wastes from the body, regulating electrolyte balance and blood pressure, and the stimulation of red blood cell production.
Kidney anatomy
illustration
-
Kidney - blood and urine flow - illustration
This is the typical appearance of the blood vessels (vasculature) and urine flow pattern in the kidney. The blood vessels are shown in red and the urine flow pattern in yellow.
Kidney - blood and urine flow
illustration
Review Date: 4/12/2023
Reviewed By: Walead Latif, MD, Nephrologist and Clinical Associate Professor, Rutgers Medical School, Newark, NJ. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.