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Proctitis

Inflammation - rectum; Rectal inflammation

Proctitis is an inflammation of the rectum. It can cause discomfort, bleeding, and the discharge of mucus or pus.

Causes

There are many causes of proctitis. They can be grouped as follows:

  • Inflammatory bowel disease
  • Autoimmune disease
  • Harmful substances
  • Non-sexually transmitted infection
  • Sexually transmitted disease (STD)

Proctitis caused by an STD is common in people who have anal intercourse. STDs that can cause proctitis include gonorrhea, herpes, chlamydia, and lymphogranuloma venereum.

Infections that are not sexually transmitted are less common than STD proctitis. One type of proctitis not from an STD is an infection in children that is caused by the same bacteria as strep throat.

Autoimmune proctitis is linked to diseases such as ulcerative colitis or Crohn disease. If the inflammation is in the rectum only, it may come and go or move upward into the large intestine.

Proctitis may also be caused by some medicines, radiotherapy to prostate or pelvis or inserting harmful substances into the rectum.

Risk factors include:

  • Autoimmune disorders, including inflammatory bowel disease
  • High-risk sexual practices, such as anal sex

Symptoms

Symptoms include:

  • Bloody stools
  • Constipation
  • Rectal bleeding
  • Rectal discharge, pus
  • Rectal pain or discomfort
  • Tenesmus (pain with bowel movement)

Exams and Tests

Tests that may be used include:

Treatment

Most of the time, proctitis will go away when the cause of the problem is treated. Antibiotics are used if an infection is causing the problem.

Corticosteroids or mesalamine suppositories or enemas may relieve symptoms for some people.

Outlook (Prognosis)

The outcome is good with treatment.

Possible Complications

Complications may include:

  • Anal fistula
  • Anemia
  • Recto-vaginal fistula (women)
  • Severe bleeding

When to Contact a Medical Professional

Contact your health care provider if you have symptoms of proctitis.

Prevention

Safe sex practices may help prevent the spread of the disease.

Open References

References

Centers for Disease Control and Prevention website. 2021 Sexually Transmitted Diseases Treatment Guidelines. www.cdc.gov/std/treatment-guidelines/proctitis.htm. Reviewed July 22, 2021. Accessed July 18, 2023.

Coates WC. Anorectum. In: Walls RM, ed. Rosen's Emergency Medicine: Concepts and Clinical Practice. 10th ed. Philadelphia, PA: Elsevier; 2023:chap 82.

Downs JM, Kulow B. Anal diseases. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger and Fordtran's Gastrointestinal and Liver Disease: Pathophysiology/Diagnosis/Management. 11th ed. Philadelphia, PA: Elsevier; 2021:chap 129.

National Institute of Diabetes and Digestive and Kidney Diseases website. Proctitis. www.niddk.nih.gov/health-information/digestive-diseases/proctitis/all-content. Updated December 2021. Accessed July 18, 2023.

  • Digestive system

    Digestive system - illustration

    The esophagus, stomach, large and small intestine, aided by the liver, gallbladder and pancreas convert the nutritive components of food into energy and break down the non-nutritive components into waste to be excreted.

    Digestive system

    illustration

  • Rectum

    Rectum - illustration

    The rectum is the final portion of the large intestine. It empties stool from the body through the anus.

    Rectum

    illustration

  • Digestive system

    Digestive system - illustration

    The esophagus, stomach, large and small intestine, aided by the liver, gallbladder and pancreas convert the nutritive components of food into energy and break down the non-nutritive components into waste to be excreted.

    Digestive system

    illustration

  • Rectum

    Rectum - illustration

    The rectum is the final portion of the large intestine. It empties stool from the body through the anus.

    Rectum

    illustration

 

Review Date: 5/2/2023

Reviewed By: Michael M. Phillips, MD, Emeritus Professor of Medicine, The George Washington University School of Medicine, Washington, DC. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

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