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Cytochrome b5 reductase

Cytochrome b5 reductase is an enzyme in the blood. It controls the amount of iron in your red blood cells, and helps the cells carry the normal amount of oxygen.

People who do not have enough of this enzyme may develop a condition called methemoglobinemia.

Open References

References

Means Jr. RT. Approach to the anemias. In: Goldman L, Cooney KA, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 144.

Smith-Whitley K, Kwiatkowski JL. Hemoglobinopathies. In: Kliegman RM, St. Geme JW, Blum NJ, et al, eds. Nelson Textbook of Pediatrics. 22nd ed. Philadelphia, PA: Elsevier; 2025:chap 511.

  • Cytochrome b5 reductase blood test

    Cytochrome b5 reductase blood test - illustration

    Cytochrome b5 reductase is a blood enzyme that serves to maintain adequate iron levels in the red blood cells to maximize their oxygen-carrying capacity.

    Cytochrome b5 reductase blood test

    illustration

  • Cytochrome b5 reductase blood test

    Cytochrome b5 reductase blood test - illustration

    Cytochrome b5 reductase is a blood enzyme that serves to maintain adequate iron levels in the red blood cells to maximize their oxygen-carrying capacity.

    Cytochrome b5 reductase blood test

    illustration

 

Review Date: 3/31/2024

Reviewed By: Todd Gersten, MD, Hematology/Oncology, Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

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