Chemotherapy
Cancer chemotherapy; Cancer drug therapy; Cytotoxic chemotherapyThe term chemotherapy is used to describe cancer-killing drugs. Chemotherapy may be used to:
- Cure the cancer
- Shrink the cancer
- Prevent the cancer from spreading
- Relieve symptoms the cancer may be causing
Information
HOW CHEMOTHERAPY IS GIVEN
Depending on the type of cancer and where it is found, chemotherapy medicines may be given different ways, including:
- Injections or shots into the muscles
- Injections or shots under the skin
- Into an artery
- Into a vein (intravenous, or IV)
- Pills taken by mouth
- Shots into the fluid around the spinal cord or brain
When chemotherapy is given over a longer period, a thin catheter can be placed into a large vein near the heart. This is called a central line. The catheter is placed during a minor surgery.
There are many types of catheters, including:
- Central venous catheter
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Central venous catheter with a port
Central venous catheter with a port
A central venous catheter is a thin tube that goes into a vein in your arm or chest and ends at the right side of your heart (right atrium). If the c...
Read Article Now Book Mark Article - Percutaneously inserted central catheter (PICC)
A central line can stay in the body over a long period of time. It will need to be flushed on a periodic basis to prevent blood clots from forming inside the central line.
Flushed
You have a central venous catheter. This is a tube that goes into a vein in your chest or neck and ends at your heart. It helps carry nutrients or ...
Different chemotherapy medicines may be given at the same time or after each other. Radiation therapy may be received before, after, or during chemotherapy.
Chemotherapy is most often given in cycles. These cycles may last 1 day, several days, or a few weeks or more. There will usually be a rest period when no chemotherapy is given between each cycle. A rest period may last for days, weeks, or months. This allows the body and blood counts to recover before the next dose.
Often, chemotherapy is given at a special clinic or at the hospital.
DIFFERENT TYPES OF CHEMOTHERAPY
The different types of chemotherapy include:
Different types of chemotherapy
Chemotherapy is the use of medicine to treat cancer. Chemotherapy kills cancer cells. It may be used to cure cancer, help keep it from spreading, o...
- Standard chemotherapy, which works by killing cancer cells and some normal cells.
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Targeted therapy, which targets a specific part of cancer cells.
Targeted therapy
Targeted therapy uses medicines to stop cancer from growing and spreading. It does this with less harm to normal cells than other treatments. Stand...
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Immunotherapy, which uses the immune system to attack cancer cells.
Immunotherapy
Immunotherapy is a type of cancer treatment that relies on the body's infection-fighting system (immune system). It uses substances made by the body...
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SIDE EFFECTS OF CHEMOTHERAPY
Because these medicines travel through the blood to the entire body, chemotherapy is described as a bodywide treatment.
As a result, chemotherapy may damage or kill some normal cells. These include bone marrow cells, hair follicles, and cells in the lining of the mouth and the digestive tract.
When this damage occurs, there can be side effects. Some people who receive chemotherapy:
- Are more likely to have infections
- Become tired more easily
- Feel pain or numbness from nerve damage
- Have a dry mouth, mouth sores, or swelling in the mouth
Dry mouth
Some cancer treatments and medicines can cause dry mouth. Take good care of your mouth during your cancer treatment. Follow the measures outlined b...
Read Article Now Book Mark ArticleSwelling in the mouth
Oral mucositis is tissue swelling and irritation in the mouth. Radiation therapy or chemotherapy may cause mucositis. Follow your health care provi...
Read Article Now Book Mark Article - Have a poor appetite or lose weight
Poor appetite or lose weight
If you are sick or undergoing cancer treatment, you may not feel like eating. But it is important to get enough protein and calories so you do not l...
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- Lose their hair
- Have problems with thinking and memory ("chemo brain")
Side effects of chemotherapy depend on many things, including the type of cancer and which drugs are being used. Each person reacts differently to these drugs. Some newer chemotherapy drugs that better target cancer cells may cause fewer or different side effects.
Your health care provider will explain what you can do at home to prevent or treat side effects. These measures include:
At home
You had chemotherapy treatment for your cancer. Your risk for infection, bleeding, and skin problems may be high. To stay healthy after chemotherap...
- Being careful with pets and other animals to avoid catching infections from them
- Eating enough calories and protein to keep your weight up
- Preventing bleeding, and what to do if bleeding occurs
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Eating and drinking safely
Eating
When you have cancer, you need good nutrition to help keep your body strong. To do this, you need to be aware of the foods you eat and how you prepa...
Read Article Now Book Mark ArticleDrinking
During and right after your cancer treatment, your body may not be able to protect itself against infections. Germs can be in water, even when it lo...
Read Article Now Book Mark Article - Washing your hands often with soap and water
You will need to have follow-up visits with your provider during and after chemotherapy. Blood tests and imaging tests, such as x-rays, MRI, CT, or PET scans will be done to:
MRI
A magnetic resonance imaging (MRI) scan is an imaging test that uses powerful magnets and radio waves to create pictures of the body. It does not us...
CT
A computed tomography (CT) scan is an imaging method that uses x-rays to create pictures of cross-sections of the body. Related tests include:Abdomin...
PET
A positron emission tomography (PET) scan is a type of imaging test. It uses a radioactive substance called a tracer to look for disease in the body...
- Monitor how well the chemotherapy is working
- Watch for damage to the heart, lungs, kidneys, blood, and other parts of the body
References
Collins JM. Cancer pharmacology. In: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. Abeloff's Clinical Oncology. 6th ed. Philadelphia, PA: Elsevier; 2020:chap 25.
Doroshow JH. Approach to the patient with cancer. In: Goldman L, Cooney K, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 164.
National Cancer Institute website. Chemotherapy to treat cancer. www.cancer.gov/about-cancer/treatment/types/chemotherapy. Updated August 23, 2022. Accessed June 18, 2024.
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Immune system structures - illustration
The immune system protects the body from potentially harmful substances. The inflammatory response (inflammation) is part of innate immunity. It occurs when tissues are injured by bacteria, trauma, toxins, heat or any other cause.
Immune system structures
illustration
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Immune system structures - illustration
The immune system protects the body from potentially harmful substances. The inflammatory response (inflammation) is part of innate immunity. It occurs when tissues are injured by bacteria, trauma, toxins, heat or any other cause.
Immune system structures
illustration
Review Date: 6/17/2024
Reviewed By: Todd Gersten, MD, Hematology/Oncology, Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.