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Enlarged liver

Hepatosplenomegaly; Enlarged liver; Liver enlargement

Enlarged liver refers to swelling of the liver beyond its normal size. Hepatomegaly is another word to describe this problem.

If both the liver and spleen are enlarged, it is called hepatosplenomegaly.

Considerations

The lower edge of the liver normally comes just to the lower edge of the ribs on the right side. The edge of the liver is normally thin and firm. It cannot be felt with the fingertips below the edge of the ribs, except when you take a deep breath. It may be enlarged if a health care provider can feel it in this area.

Causes

The liver is involved in many of the body's functions. Its function is affected by many conditions that can cause hepatomegaly, including:

When to Contact a Medical Professional

This condition is most often detected by a provider. You may not be aware of the liver or spleen swelling.

What to Expect at Your Office Visit

The provider will examine you and ask questions such as:

  • Did you notice fullness or a lump in the abdomen?
  • What other symptoms do you have?
  • Is there any abdominal pain?
  • Is there any yellowing of the skin (jaundice)?
  • Is there any vomiting?
  • Is there any unusual-colored or pale-colored stools?
  • Has your urine appeared to be darker than usual (brownish)?
  • Have you had a fever?
  • What medicines are you taking including over-the-counter and herbal medicines?
  • How much alcohol do you drink?

Tests to determine the cause of hepatomegaly vary, depending on the suspected cause, but may include:

Open References

References

Martin P. Approach to the patient with liver disease. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 137.

Plevris J, Parks R. The gastrointestinal system. In: Dover AR, Innes JA , Fairhurst K, eds. Macleod's Clinical Examination. 15th ed. Philadelphia, PA: Elsevier; 2024:chap 6.

Squires JE, Balistreri WF. Manifestations of liver disease. In: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Textbook of Pediatrics. 21st ed. Philadelphia, PA: Elsevier; 2020:chap 382.

  • Fatty liver - CT scan

    Fatty liver - CT scan - illustration

    A CT scan of the upper abdomen showing a fatty liver (steatosis of the liver). Note the liver enlargement and dark color compared with the spleen (gray body in lower right).

    Fatty liver - CT scan

    illustration

  • Liver with disproportional fattening - CT scan

    Liver with disproportional fattening - CT scan - illustration

    A CT scan of the upper abdomen showing disproportional steatosis (fattening) of the liver.

    Liver with disproportional fattening - CT scan

    illustration

  • Hepatomegaly

    Hepatomegaly - illustration

    Hepatomegaly is enlargement of the liver beyond its normal size. Certain conditions such as infection, parasites, tumors, anemias, toxic states, storage diseases, heart failure, congenital heart disease, and metabolic disturbances may all cause an enlarged liver.

    Hepatomegaly

    illustration

  • Fatty liver - CT scan

    Fatty liver - CT scan - illustration

    A CT scan of the upper abdomen showing a fatty liver (steatosis of the liver). Note the liver enlargement and dark color compared with the spleen (gray body in lower right).

    Fatty liver - CT scan

    illustration

  • Liver with disproportional fattening - CT scan

    Liver with disproportional fattening - CT scan - illustration

    A CT scan of the upper abdomen showing disproportional steatosis (fattening) of the liver.

    Liver with disproportional fattening - CT scan

    illustration

  • Hepatomegaly

    Hepatomegaly - illustration

    Hepatomegaly is enlargement of the liver beyond its normal size. Certain conditions such as infection, parasites, tumors, anemias, toxic states, storage diseases, heart failure, congenital heart disease, and metabolic disturbances may all cause an enlarged liver.

    Hepatomegaly

    illustration

Tests for Enlarged liver

 
 

Review Date: 5/2/2023

Reviewed By: Michael M. Phillips, MD, Emeritus Professor of Medicine, The George Washington University School of Medicine, Washington, DC. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

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