Open pleural biopsy
Biopsy - open pleuraAn open pleural biopsy is a procedure to remove and examine the tissue that lines the inside of the chest. This tissue is called the pleura.
How the Test is Performed
An open pleural biopsy is done in the hospital using general anesthesia. This means you will be asleep and pain free. A tube will be placed through your mouth down your throat into your windpipe (trachea) to help you breathe.
General anesthesia
General anesthesia is treatment with certain medicines that puts you into a deep sleep so you do not feel pain during surgery. After you receive the...
The surgery is done in the following way:
- After cleaning the skin, the surgeon makes a small cut in the left or right side of the chest.
- The ribs are gently separated.
- A scope may be inserted to see the area to be biopsied.
- Tissue is taken from inside the chest and sent to a laboratory for examination.
- After surgery, the wound is closed with stitches.
- Your surgeon may decide to leave a small plastic tube in your chest to prevent air and fluid from building up.
The breathing tube may not be able to be removed right after surgery. So, you may need to be on a breathing machine for some time.
Breathing machine
A ventilator is a machine that breathes for you or helps you breathe. It is also called a breathing machine or respirator. The ventilator: Is attac...
How to Prepare for the Test
You should tell your surgeon if you are pregnant, allergic to any medicines, or if you have a bleeding problem. Be sure to tell your health care provider about all the medicines you take, including herbs, supplements, and those bought without a prescription.
Follow your surgeon's instructions for not eating or drinking before the procedure.
How the Test will Feel
When you wake up after the procedure, you will feel drowsy for several hours.
There will be some tenderness and pain where the surgical cut is located. Most surgeons inject a long-acting local anesthetic at the surgical cut site so that you will have very little pain afterward.
You may have a sore throat from the breathing tube. You can ease the pain by eating ice chips.
You may have a tube in your chest to remove air. This will be removed later.
Why the Test is Performed
This procedure is used when the surgeon needs a larger piece of tissue than can be removed with a pleural needle biopsy. The test is most often done to rule out mesothelioma, a type of lung tumor.
Pleural needle biopsy
Pleural biopsy is a procedure to remove a sample of the pleura. This is the thin tissue that lines the chest cavity and surrounds the lungs. The bi...
Mesothelioma
Malignant mesothelioma is an uncommon cancerous tumor. It mainly affects the lining of the lung and chest cavity (pleura) or lining of the abdomen (...
It is also done when there is fluid in the chest cavity, or when a direct view of the pleura and the lungs is needed.
This procedure may also be done to examine a metastatic pleural tumor. This is a type of cancer that has spread from another organ to the pleura.
Metastatic pleural tumor
Metastatic pleural tumor is a type of cancer that has spread from another organ to the thin membrane (pleura) surrounding the lungs.
Normal Results
The pleura will be normal.
What Abnormal Results Mean
Abnormal findings may be due to:
- Abnormal tissue growth (neoplasms)
Neoplasms
A tumor is an abnormal growth of body tissue. Tumors can be cancerous (malignant) or noncancerous (benign).
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- Mesothelioma
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Tuberculosis
Tuberculosis
Pulmonary tuberculosis (TB) is a contagious bacterial infection that involves the lungs. It may spread to other organs.
Risks
There is a slight chance of:
- Air leak
- Excess blood loss
- Infection
- Injury to the lung
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Pneumothorax (collapsed lung)
Pneumothorax
A collapsed lung occurs when air escapes from the lung. The air then fills the space outside of the lung between the lung and chest wall. This buil...
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References
Chernecky CC, Berger BJ. Biopsy, site-specific - specimen. In: Chernecky CC, Berger BJ, eds. Laboratory Tests and Diagnostic Procedures. 6th ed. St Louis, MO: Elsevier Saunders; 2013:199-202.
Wald O, Izhar U, Sugarbaker DJ. Lung, chest wall, pleura and mediastinum. In: Townsend CM Jr, Beauchamp RD, Evers BM, Mattox KL, eds. Sabiston Textbook of Surgery. 21st ed. St Louis, MO: Elsevier; 2022:chap 58.
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Lungs - illustration
The major features of the lungs include the bronchi, the bronchioles and the alveoli. The alveoli are the microscopic blood vessel-lined sacks in which oxygen and carbon dioxide gas are exchanged.
Lungs
illustration
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Incision for pleural tissue biopsy - illustration
In an open pleural biopsy, a small piece of the pleural tissue is removed through a surgical incision in the chest. After the sample is obtained, a chest tube is placed and the incision is closed with stitches. Abnormal results may indicate tuberculosis, abnormal growths, viral, fungal, and parasitic diseases.
Incision for pleural tissue biopsy
illustration
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Pleural cavity - illustration
The pleural cavity is composed of the layers of the membrane lining the lung and the chest cavity.
Pleural cavity
illustration
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Lungs - illustration
The major features of the lungs include the bronchi, the bronchioles and the alveoli. The alveoli are the microscopic blood vessel-lined sacks in which oxygen and carbon dioxide gas are exchanged.
Lungs
illustration
-
Incision for pleural tissue biopsy - illustration
In an open pleural biopsy, a small piece of the pleural tissue is removed through a surgical incision in the chest. After the sample is obtained, a chest tube is placed and the incision is closed with stitches. Abnormal results may indicate tuberculosis, abnormal growths, viral, fungal, and parasitic diseases.
Incision for pleural tissue biopsy
illustration
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Pleural cavity - illustration
The pleural cavity is composed of the layers of the membrane lining the lung and the chest cavity.
Pleural cavity
illustration
Review Date: 10/10/2022
Reviewed By: Mary C. Mancini, MD, PhD, Cardiothoracic Surgeon, Shreveport, LA. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.