Transient tachypnea - newborn
TTN; Wet lungs - newborns; Retained fetal lung fluid; Transient RDS; Prolonged transition; Neonatal - transient tachypneaTransient tachypnea of the newborn (TTN) is a breathing disorder seen shortly after delivery, most often in early term or late preterm babies.
- Transient means it is short-lived (most often less than 48 hours).
- Tachypnea means rapid breathing (faster than most newborns, who normally breathe 40 to 60 times per minute).
Causes
As the baby grows in the womb (uterus), the lungs make a special fluid. This fluid fills the baby's lungs and helps them grow. When the baby is born at term, hormones released during labor tell the lungs to stop making this special fluid. The baby's lungs start removing or reabsorbing it.
The first few breaths a baby takes after delivery fill the lungs with air and help to clear most of the remaining lung fluid.
Leftover fluid in the lungs causes the baby to breathe rapidly. It is harder for the small air sacs of the lungs to stay open.
TTN is more likely to occur in babies who are:
- Born before 38 completed weeks gestation (preterm, or early term)
- Delivered by C-section, especially if labor has not already started
C-section
A C-section is the delivery of a baby by making an opening in the mother's lower belly area. It is also called a cesarean delivery.
Read Article Now Book Mark Article - Born to a mother with diabetes or asthma
Diabetes
Diabetes is a long-term (chronic) disease in which the body cannot regulate the amount of sugar in the blood.
Read Article Now Book Mark ArticleAsthma
Asthma is a chronic disease that causes the airways of the lungs to swell and narrow. It leads to breathing difficulty such as wheezing, shortness o...
Read Article Now Book Mark Article - Twins
Symptoms
Newborns with TTN have breathing problems soon after birth, usually starting within 1 to 2 hours.
Symptoms include:
- Bluish skin color (cyanosis)
Cyanosis
A bluish color to the skin or mucous membrane is usually due to a lack of oxygen in the blood. The medical term is cyanosis.
Read Article Now Book Mark Article -
Rapid breathing, which may occur with noises such as grunting
Rapid breathing
A normal breathing rate for an adult at rest is 12 to 20 breaths per minute. For an infant, a normal rate is 30 to 60 breaths per minute. Tachypnea ...
Read Article Now Book Mark Article - Flaring nostrils or movements between the ribs or breastbone known as retractions
Exams and Tests
The mother's pregnancy and labor history are important to make the diagnosis.
Tests performed on the baby may include:
-
Blood count and blood culture to rule out infection
Blood count
A complete blood count (CBC) test measures the following:The number of white blood cells (WBC count)The number of red blood cells (RBC count)The numb...
Read Article Now Book Mark ArticleBlood culture
A blood culture is a laboratory test to check for bacteria or other germs in a blood sample.
Read Article Now Book Mark Article -
Chest x-ray to rule out other causes of breathing problems
Chest x-ray
A chest x-ray is an x-ray of the chest, lungs, heart, large arteries, ribs, and diaphragm.
Read Article Now Book Mark Article - Blood gas to check levels of carbon dioxide and oxygen
- Continuous monitoring of the baby's oxygen levels, breathing, and heart rate
The diagnosis of TTN is most often made after the baby is monitored for 2 or 3 days. If the condition goes away in that time, it is considered to be transient.
Treatment
Your baby will be given oxygen, and sometimes CPAP (continuous positive airway pressure) as well, to keep the blood oxygen level and breathing rate stable. Your baby will often need the most support within a few hours after birth and will usually begin to improve after that. Most infants with TTN improve in less than 24 to 48 hours, but some will need help for a few days.
Very rapid breathing usually means a baby is unable to eat. Fluids and nutrients will be given through a vein until your baby improves. Your baby may also receive antibiotics if there is concern for infection. Sometimes, babies with TTN will need help with breathing or feeding for a week or more, usually if they are premature.
Outlook (Prognosis)
The condition most often goes away within 48 to 72 hours after delivery. In most cases, babies who have had TTN have no further problems from the condition. They will not need special care or follow-up other than their routine checkups. However, there is some evidence that babies with TTN may be at a higher risk for wheezing problems later in infancy.
References
Ahlfeld SK. Respiratory tract disorders. In: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Textbook of Pediatrics. 21st ed. Philadelphia, PA: Elsevier; 2020:chap 122.
Crowley MA. Spectrum of neonatal respiratory disorders. In: Martin RJ, Fanaroff AA, eds. Fanaroff and Martin's Neonatal-Perinatal Medicine: Diseases of the Fetus and Infant. 12th ed. Philadelphia, PA: Elsevier; 2025:chap 67.
Review Date: 12/31/2023
Reviewed By: Mary J. Terrell, MD, IBCLC, Neonatologist, Cape Fear Valley Medical Center, Fayetteville, NC. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
All rights reserved.