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Charcot foot

Charcot joint; Neuropathic arthropathy; Charcot neuropathic osteoarthropathy; Charcot arthropathy; Charcot osteoarthropathy; Diabetic Charcot foot

Charcot foot is a condition that affects the bones, joints, and soft tissue in the feet and ankles. It can develop as a result of nerve damage in the feet due to diabetes or other nerve injuries.

Causes

Charcot foot is a rare and disabling disorder. It is a result of nerve damage to the feet. A common cause is peripheral neuropathy.

Diabetes is the most common cause of this type of nerve damage. This damage is more common in people with type 1 diabetes. When blood sugar levels are high over a long time, both nerve and blood vessel damage occurs in the arms and legs.

Nerve damage makes it harder to notice the amount of pressure on the foot or if it is being stressed. The result is ongoing small injuries to the bones and ligaments that support the foot.

  • You may develop bone stress fractures in your feet, yet never know it.
  • Continuing to walk on the fractured bone often leads to further bone and joint damage.

Other factors leading to foot damage include:

  • Blood vessel damage from diabetes can increase or change blood flow to the feet. This can lead to bone loss. Weakened bones in the feet increase the risk of fracture.
  • Injury to the foot signals the body to produce more inflammation-causing chemicals. This contributes to swelling and bone loss.

Symptoms

Early foot symptoms may include:

  • Mild pain and discomfort
  • Redness
  • Swelling
  • Warmth in the affected foot (noticeably warmer than the other foot)

At later stages, bones in the foot break and move out of place, causing the foot or ankle to become deformed.

  • A classic sign of Charcot is rocker-bottom foot. This occurs when the bones in middle of the foot collapse. This causes the arch of the foot to collapse and bow downward.
  • The toes may curl downward.

Bones that stick out at odd angles can lead to pressure sores and foot ulcers.

  • Because the feet are numb, these sores and ulcers may grow wider or deeper before they are noticed.
  • High blood sugar also makes it hard for the body to fight infection. As a result, these foot ulcers may become infected.

Exams and Tests

Charcot foot is not always easy to diagnose early on. It can be mistaken for sprains, bone infection, arthritis or joint swelling. Your health care provider will take your medical history and examine your foot and ankle.

Blood tests and other lab work may be done to help rule out other causes.

Your provider may check for nerve damage with these tests:

The following tests may be done to check for bone and joint damage:

Foot x-rays may look normal at early stages of the condition. Diagnosis often comes down to recognizing early symptoms of Charcot foot: swelling, redness, and warmth of the affected foot.

Treatment

The goal of treatment is to stop bone loss, allow bones to heal, and prevent bones from moving out of place (deformity).

Immobilization -- Your provider will have you wear a total contact cast. This will help limit movement of your foot and ankle. You will likely be asked to keep your weight off your foot entirely, so you will need to use crutches, a knee-walker device, or wheelchair.

You will have new casts placed on your foot as the swelling comes down. Healing can take a couple of months or more.

Protective footwear -- Once your foot has healed, your provider may suggest footwear to help support your foot and prevent re-injury. These may include:

  • Splints
  • Braces
  • Orthotic insoles
  • Charcot restraint orthotic walker, a special boot that provides even pressure to the whole foot

Activity changes -- You will always be at risk for Charcot foot coming back or developing in your other foot. So your provider may recommend activity changes, such as limiting your standing or walking, to protect your feet. You may need to use a wheelchair to limit activity on your feet.

Surgery -- You may need surgery if you have foot ulcers that keep coming back or severe foot or ankle deformity. Surgery can help stabilize your foot and ankle joints and remove bony areas to prevent foot ulcers.

Ongoing monitoring -- You will need to see your provider for checkups and take steps to protect your feet for the rest of your life.

Outlook (Prognosis)

The prognosis depends on the severity of foot deformity and how well you heal without infection. Many people do well with braces, activity changes, and ongoing monitoring.

Possible Complications

Severe deformity of the foot increases the risk of foot ulcers. If ulcers or the underlying bone becomes infected and hard to treat, it may require amputation.

When to Contact a Medical Professional

Contact your provider if you have diabetes and your foot is warm, red, or swollen.

Prevention

Healthy habits can help prevent or delay Charcot foot:

  • Keep good control of your blood glucose levels to help prevent or delay Charcot foot. But it can still occur, even in people with good diabetes control.
  • Take care of your feet. Check them every day.
  • See your foot doctor regularly.
  • Check your feet regularly to look for cuts, redness and sores.
  • Avoid injuring your feet.
Open References

References

Baxi O, Yeranosian M, Lin A, Munoz M, Lin S. Orthotic management of neuropathic and dysvascular feet. In: Webster JB, Murphy DP, eds. Atlas of Orthoses and Assistive Devices. 5th ed. Philadelphia, PA: Elsevier; 2019:chap 26.

Brownlee M, Aiello LP, Sun JK, et al. Complications of diabetes mellitus. In: Melmed S, Auchus RJ, Goldfine AB, Koenig RJ, Rosen CJ, eds. Williams Textbook of Endocrinology. 14th ed. Philadelphia, PA: Elsevier; 2020:chap 37.

ElSayed NA, Aleppo G, Aroda VR, et al, on behalf of the American Diabetes Association. 12. Retinopathy, Neuropathy, and Foot Care: Standards of Care in Diabetes-2023. Diabetes Care. 2023 1;46(Suppl 1):S203-S215. PMID: 36507636; PMCID: PMC9810462. pubmed.ncbi.nlm.nih.gov/36507636/.

  • Diabetes

    Animation

    •  

    Diabetes - Animation

    Diabetes is on the rise worldwide, and is a serious, lifelong disease that can lead to heart disease, stroke, and lasting nerve, eye and foot problems. Let's talk about diabetes and the difference between the three types of diabetes. So, what exactly is diabetes and where does it come from? An organ in your body called the pancreas produces insulin, a hormone that controls the levels of your blood sugar. When you have too little insulin in your body, or when insulin doesn't work right in your body, you can have diabetes, the condition where you have abnormally high glucose or sugar levels in your blood. Normally when you eat food, glucose enters your bloodstream. Glucose is your body's source of fuel. Your pancreas makes insulin to move glucose from your bloodstream into muscle, fat, and liver cells, where your body turns it into energy. People with diabetes have too much blood sugar because their body cannot move glucose into fat, liver, and muscle cells to be changed into and stored for energy. There are three major types of diabetes. Type 1 diabetes happens when the body makes little or no insulin. It usually is diagnosed in children, teens, or young adults. But about 80% of people with diabetes have what's called Type 2 diabetes. This disease often occurs in middle adulthood, but young adults, teens, and now even children are now being diagnosed with it linked to high obesity rates. In Type 2 diabetes, your fat, liver, and muscle cells do not respond to insulin appropriately. Another type of diabetes is called gestational diabetes. It's when high blood sugar develops during pregnancy in a woman who had not had diabetes beforehand. Gestational diabetes usually goes away after the baby is born. But, still pay attention. These women are at a higher risk of type 2 diabetes over the next 5 years without a change in lifestyle. If you doctor suspects you have diabetes, you will probably have a hemoglobin A1c test. This is an average of your blood sugar levels over 3 months. You have pre-diabetes if your A1c is 5.7% to 6.4%. Anything at 6.5% or higher indicates you have diabetes. Type 2 diabetes is a wake up call to focus on diet and exercise to try to control your blood sugar and prevent problems. If you do not control your blood sugar, you could develop eye problems, have problems with sores and infections in your feet, have high blood pressure and cholesterol problems, and have kidney, heart, and problems with other essential organs. People with Type 1 diabetes need to take insulin every day, usually injected under the skin using a needle. Some people may be able to use a pump that delivers insulin to their body all the time. People with Type 2 diabetes may be able to manage their blood sugar through diet and exercise. But if not, they will need to take one or more drugs to lower their blood sugar levels. The good news is, people with any type of diabetes, who maintain good control over their blood sugar, cholesterol, and blood pressure, have a lower risk of kidney disease, eye disease, nervous system problems, heart attack, and stroke, and can live, a long and healthy life.

  • Nerve conduction test

    Nerve conduction test - illustration

    The nerve conduction velocity test is performed to evaluate nerve function. It tests the speed impulses travel through a nerve.

    Nerve conduction test

    illustration

  • Diabetes and nerve damage

    Diabetes and nerve damage - illustration

    Diabetes can damage the nerves and cause a complication called neuropathy. This generally begins as loss of sensation in the toes, and possibly fingers. Eventually, the neuropathy can move up the person's legs or arms. Nerve damage results in decreased ability to feel pain, pressure, and extremes of temperature.

    Diabetes and nerve damage

    illustration

  • Diabetic foot care

    Diabetic foot care - illustration

    People with diabetes are prone to foot problems because the disease can cause damage to the blood vessels and nerves, which may result in decreased ability to sense a trauma to the foot. The immune system is also altered, so that the person with diabetes cannot efficiently fight infection.

    Diabetic foot care

    illustration

  • Diabetes

    Animation

    •  

    Diabetes - Animation

    Diabetes is on the rise worldwide, and is a serious, lifelong disease that can lead to heart disease, stroke, and lasting nerve, eye and foot problems. Let's talk about diabetes and the difference between the three types of diabetes. So, what exactly is diabetes and where does it come from? An organ in your body called the pancreas produces insulin, a hormone that controls the levels of your blood sugar. When you have too little insulin in your body, or when insulin doesn't work right in your body, you can have diabetes, the condition where you have abnormally high glucose or sugar levels in your blood. Normally when you eat food, glucose enters your bloodstream. Glucose is your body's source of fuel. Your pancreas makes insulin to move glucose from your bloodstream into muscle, fat, and liver cells, where your body turns it into energy. People with diabetes have too much blood sugar because their body cannot move glucose into fat, liver, and muscle cells to be changed into and stored for energy. There are three major types of diabetes. Type 1 diabetes happens when the body makes little or no insulin. It usually is diagnosed in children, teens, or young adults. But about 80% of people with diabetes have what's called Type 2 diabetes. This disease often occurs in middle adulthood, but young adults, teens, and now even children are now being diagnosed with it linked to high obesity rates. In Type 2 diabetes, your fat, liver, and muscle cells do not respond to insulin appropriately. Another type of diabetes is called gestational diabetes. It's when high blood sugar develops during pregnancy in a woman who had not had diabetes beforehand. Gestational diabetes usually goes away after the baby is born. But, still pay attention. These women are at a higher risk of type 2 diabetes over the next 5 years without a change in lifestyle. If you doctor suspects you have diabetes, you will probably have a hemoglobin A1c test. This is an average of your blood sugar levels over 3 months. You have pre-diabetes if your A1c is 5.7% to 6.4%. Anything at 6.5% or higher indicates you have diabetes. Type 2 diabetes is a wake up call to focus on diet and exercise to try to control your blood sugar and prevent problems. If you do not control your blood sugar, you could develop eye problems, have problems with sores and infections in your feet, have high blood pressure and cholesterol problems, and have kidney, heart, and problems with other essential organs. People with Type 1 diabetes need to take insulin every day, usually injected under the skin using a needle. Some people may be able to use a pump that delivers insulin to their body all the time. People with Type 2 diabetes may be able to manage their blood sugar through diet and exercise. But if not, they will need to take one or more drugs to lower their blood sugar levels. The good news is, people with any type of diabetes, who maintain good control over their blood sugar, cholesterol, and blood pressure, have a lower risk of kidney disease, eye disease, nervous system problems, heart attack, and stroke, and can live, a long and healthy life.

  • Nerve conduction test

    Nerve conduction test - illustration

    The nerve conduction velocity test is performed to evaluate nerve function. It tests the speed impulses travel through a nerve.

    Nerve conduction test

    illustration

  • Diabetes and nerve damage

    Diabetes and nerve damage - illustration

    Diabetes can damage the nerves and cause a complication called neuropathy. This generally begins as loss of sensation in the toes, and possibly fingers. Eventually, the neuropathy can move up the person's legs or arms. Nerve damage results in decreased ability to feel pain, pressure, and extremes of temperature.

    Diabetes and nerve damage

    illustration

  • Diabetic foot care

    Diabetic foot care - illustration

    People with diabetes are prone to foot problems because the disease can cause damage to the blood vessels and nerves, which may result in decreased ability to sense a trauma to the foot. The immune system is also altered, so that the person with diabetes cannot efficiently fight infection.

    Diabetic foot care

    illustration

 

Review Date: 12/12/2022

Reviewed By: C. Benjamin Ma, MD, Professor, Chief, Sports Medicine and Shoulder Service, UCSF Department of Orthopaedic Surgery, San Francisco, CA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

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