Remestemcel-l-rknd (By injection)

Remestemcel-L-rknd (rem-e-STEM-sel - el - rknd)

Treats acute graft-versus-host disease (GVHD).

Brand Name(s):

When This Medicine Should Not Be Used:

How to Use This Medicine:

Injectable

• Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein. This medicine must be given slowly, so the IV will need to stay in place for at least 60 minutes.
• A nurse or other health provider will give you this medicine.
• Your child may also receive other medicines (including allergy medicine or steroid) 30 to 60 minutes before receiving this medicine.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Warnings While Using This Medicine:

• Tell your child's doctor if your child is pregnant or breastfeeding.
• This medicine may cause the following problems:
  • Infusion reactions
  • Increased risk of ectopic tissue formation (tissue growth outside normal location)
• This medicine is made from donated human blood. Some human blood products have transmitted certain viruses (including HIV, hepatitis B or C) or genetic diseases to people who have received them, although the risk is low.
• Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Bleeding gums, coughing up blood, headache, nosebleeds, trouble breathing
• Blurred vision, dizziness, nervousness, pounding in the ears, slow or fast heartbeat
• Fever, chills, cough, sore throat, body aches
• Rapid weight gain, swelling in your hands, ankles, or feet

If you notice these less serious side effects, talk with your doctor:

• Stomach pain

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 3/4/2025